Ex vivo drug screening on patient-derived tumor material to advance functional precision in oncology: an overview on current approaches and unresolved challenges
- Authors
- Spiró Z, El-Heliebi A, Mair MJ, Pieber TR, Prietl B, Spiegl-Kreinecker S, Stanzer S, Wöhrer A, Preusser M, Berghoff AS. Ex vivo drug screening on patient- derived tumor material to advance functional precision in oncology: an overview on current approaches and unresolved challenges. Cancer Treat Rev. 2026 Feb;143:103072. doi: 10.1016/j.ctrv.2025.103072. Epub 2025 Dec 22. PMID: 41475298.
- Journal
- Cancer Treatment Reviews
- Published
Abstract
This review summarizes current approaches to ex vivo drug screening on patient derived tumor material. It also discusses unresolved challenges limiting broader clinical implementation. Technologies used at CBmed: drug screening and cell culture and advanced data analysis.