WE AIM TO REDUCE THE BURDEN OF CARDIO-METABOLIC DISEASE
Cardiovascular disease (CVD) is a major public health problem. Although the mortality rates of CVD have decreased substantially over the last decade, almost half of all deaths are still attributed to CVD. Biomarker-guided cardiovascular disease risk prediction, biomarker-based treatment selection, and response monitoring have been proposed in recent years, but the addition of a set of biomarkers to establish risk scores has been moderately successful in improving cardiovascular risk prediction.
Obesity and diabetes likely represent the most challenging threat to public health in the 21st century. The main contributing factors for developing type 2 diabetes range from nutritional habits and sedentary lifestyle causing insulin resistance, but also include factors like genetic/epigenetic predisposition. The overall aim of this project is to investigate biomarkers for cardiovascular disease (CVD) risk prediction, response to treatment, and cardiovascular-related risk conditions.